Administration of hormones:

The body has a complex self-regulating system. The amount of hormone released by an endocrine gland is determined by the body's need of the hormone at that particular time. Cells that produce hormones are regulated by a feedback system from the body and that helps it to release just the right amount of the hormone into the body. This system stops over-release or under-release of each hormone.

However, when the body receives a source of hormone from outside the body,such as a prescription of the actual hormone, the body will slow down or stop it's own production of the hormone over a period of time. This is true even if it is a "naturally-derived" source and the end result over long term use can mean glandular shutdown.

This may not be a concern in elderly people (80+ years old) but in younger people under 80 years, this can lead to serious problems. Concerns of direct injection of synthesized recombinant hGH causing cancer growth is another major problem with the hormone used on a long term basis.

Hormone Releasers:

A better way to optimise the hormone/endocrine system is to stimulate the gland to produce the hormone itself and to give your body the right "building blocks" (nutrients such as amino acids) for production of its necessary hormones. In this way, you allow the body's developed feedback system to work unhindered without risking glandular atrophy or other problems. This also prevents over-dosing on the hormone as is quite possible with taking hormone itself. It helps your glands to strengthen and allow the correct hormone to be released at the level which the body needs.